How Alnylam is transforming its sustainability data management with Sprih

Alnylam’s strategic partnership with Sprih ushered in a transformative shift in the management of its sustainability data.

This case study explores how Sprih’s tailored approach and deep expertise helped Alnylam streamline complex data processes, ensure global compliance, and lead with confidence in the pharmaceutical sector’s sustainability landscape.

Working with Sprih, Alnylam has accelerated its sustainability journey by integrating cutting-edge technology and expert insights. This collaboration has enabled us to optimize emissions tracking and confidently navigate complex global regulations, setting a new benchmark.

- Jeffrey Richards, Senior Director, EHS Alnylam Pharmaceuticals
Introduction

In an era where the intersection of science, equity, and sustainability is more critical than ever, Alnylam is a leading biotechnology company committed to delivering transformative health solutions while driving meaningful societal and environmental impact. Rooted in its pioneering RNAi platform, the company embraces a holistic approach to corporate responsibility - one that prioritizes not just scientific innovation, but also access to care, climate action, and inclusive growth.

Alnylam’s sustainability initiative reflects its commitment to advancing RNAi therapeutics while fostering a healthier, more equitable, and sustainable world. Centered around six core pillars - Patients, Science, Employees, Communities, Planet, and Governance - the company emphasizes patient access, innovation in rare and prevalent diseases, workplace inclusivity, and global community engagement. Key achievements include third-party verified emissions data, green power purchase agreements for their two manufacturing sites, and expanded access to therapies in over 70 countries. Alnylam’s integrated approach to corporate responsibility aligns with global sustainability standards and showcases its dedication to long-term social and environmental impact.

Alnylam: Scale and Scope

Global Presence
21+
Locations
Emission Sources
100+
Across Operations
Emission Factors
174+
Including Custom EFs
Avg. Data Points
25,000+
Per Month
Challenges

The Hurdles in Alnylam's Path

Alnylam started early on their path to driving investments in sustainability initiatives as a growing company in the biotechnology sector. As the process evolved, the need to move to a systemic platform and away from manual data collection and processing became evident very quickly. The challenges and opportunities included:
  • Streamlining Workflows for Efficiency
    Coordinating data across 21 locations and multiple stakeholders, while largely relying on spreadsheets and emails, meant significant administrative strain, and room for delays and errors.
  • Leveraging Technology for Scalable Growth
    Alnylam saw the value in moving beyond manual processing to a long-term, tech-driven system - one that ensures continuity, drives on-ground action, and offers real-time visibility so teams can focus on impact.
  • Enhancing Real-Time Data Accessibility
    Submitted data lacked traceability and verification. Alnylam needed audit trails and real-time validation to improve data consistency and quality.
  • Navigating Complex Global Compliance
    As global operations grew, so did regulatory complexity. Alnylam sought a scalable solution to meet compliance requirements efficiently, without burdening internal teams.
  • Unlocking Insights for Strategic Decisions
    Spreadsheets limited Alnylam’s ability to track trends, benchmark performance, and forecast effectively. Better analytics were essential to turn reporting into a strategic advantage.

Looking for Answers to…

Automate and tech-enable processes
Ensure compliance with global regulations
Gain deeper insights for better decisions
Achieve real-time visibility into data quality
Track evolving global compliance regularly
Solutions

Sprih’s Comprehensive Approach

  • Tailored, Not Off-the-Shelf: We configured our platform to fit Alnylam’s unique processes—no one-size-fits-all solutions.
  • In-Depth Emission Source Analysis: Conducted a thorough study of their emission sources and aligned the system to their specific needs.
  • Expert-Led Data Gap Assessment: Engaged domain specialists to identify and bridge critical data gaps for accuracy.
  • Geo-Specific Compliance Alignment: Incorporated region-specific emission factors to meet global regulatory demands precisely.
  • Actionable, Customer-Centric Insights: Delivered intuitive visualizations and insights designed to drive informed decisions and real impact.

Sprih’s Solutions Transform Alnylam’s Sustainability Data Management

01

End-to-End Automation: Sprih transformed manual workflows into fully automated processes, minimizing time and errors.

02

Aligned with the Biotech Needs:
Expanded emissions coverage by integrating sector-specific sources and custom Emission Factors tailored to biotech operations.

03

Transparent Audit Trails: Enabled full data traceability and real-time issue detection for improved audit readiness.

04

AI-Powered Insights: Leveraged advanced analytics to uncover deep, actionable sustainability intelligence.

05

Global Compliance Expertise: Provided ongoing compliance tracking tailored to complex, multi-country regulatory landscapes.
Impact

Measurable Business Benefits

6X Faster
From data collection to processing.
High Data Quality
Advanced AI checks for near-zero data errors.
Audit Ready
Region-specific emission factors, transparent methods, complete audit trails.

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